Pain lasts longer in women, and immune cells may be the culprit

undefined 3, 2026

Source: mos

New research suggests women may experience longer-lasting pain than men due to differences in immune cell function. Immune cells called monocytes produce interleukin-10 (IL-10), which helps turn off pain signals. In men, higher testosterone boosts IL-10 production, aiding faster recovery. In women, this response is weaker, potentially explaining greater chronic pain risk. Understanding these immune pathways could lead to therapies that enhance the body’s natural pain-resolution system.

Share on